Journal Club
病理診断科では、毎週月曜日に抄読会を開催しております．
抄読会で提示した内容はこのページで随時公開していきます．
2024年
| 2024/02/16 |
Histone demethylase KDM5D upregulation drives sex differences in colon cancer 詳細はこちら  (PDF:366KB)
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| 2024/02/09 |
miRNA levels are associated with body mass index in endometrial cancer and may have implications for therapy. 詳細はこちら (PDF:1013KB)
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| 2024/01/19 |
Patterns of transcription factor programs and immune pathway activation define four major subtypes of SCLC with distinct therapeutic vulnerabilities 詳細はこちら (PDF:1433KB)
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| 2024/01/12 |
S100-stained perineural invasion is associated with worse prognosis in stage I/II colorectal cancer: Its possible association with immunosuppression in the tumor 詳細はこちら (PDF:973KB)
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2023年
| 2023/12/15 |
p16 overexpression and Rb loss correlate with high-risk HPV infection in oropharyngeal squamous cell carcinoma 詳細はこちら (PDF:1973KB)
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| 2023/12/01 |
Diagnostic challenges of intra-operative frozen consultation for gastrointestinal signet ring cell carcinoma 詳細はこちら (PDF:448KB)
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| 2023/11/24 |
High-grade vulvar intraepithelial neoplasia: comprehensive characterization and long-term vulvar carcinoma risk 詳細はこちら (PDF:1859KB)
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| 2023/11/17 |
Non-diffuse large B-cell lymphoma transformation from follicular lymphoma: a single-institution study of 19 cases 詳細はこちら (PDF:623KB)
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| 2023/10/27 |
First-Line Genomic Profiling in Previously Untreated Advanced Solid Tumors for Identification of Targeted Therapy Opportunities. 詳細はこちら (PDF:1520KB)
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| 2023/10/12 |
The risk of weekend biopsy: Impact of specimen source and fixation status on HER2 assessment in the treatment of advanced gastric cancer (The HER_WEEKEND study) 詳細はこちら (PDF:891KB)
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| 2023/10/06 |
Worst pattern of invasion in oral squamous cell carcinoma is an independent prognostic factor. 詳細はこちら (PDF:875KB)
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| 2023/09/22 |
Getting it Right the First Time: Frozen Sections for Diagnosing Necrotizing Soft Tissue Infections 詳細はこちら (PDF:1078KB)
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| 2023/09/15 |
Cause of death and the autopsy rate in an elderly population. 詳細はこちら (PDF:794KB)
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| 2023/09/08 |
Review of lymphoma in the duodenum: An update of diagnosis and management 詳細はこちら (PDF:1161KB)
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| 2023/09/01 |
Hypothesis: HEG1 and claudin-4 staining will allow a diagnosis of epithelioid and biphasic mesothelioma versus non-small-cell lung carcinoma with only two stains in most cases 詳細はこちら (PDF:1185KB)
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| 2023/08/25 |
Cancer-Associated Fibroblasts in Mycosis Fungoides Promote Tumor Cell Migration and Drug Resistance through CXCL12/CXCR4 詳細はこちら (PDF:558KB)
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| 2023/08/18 |
Can dual staining with p16 and Ki67 be biomarkers of epithelial dysplasia in oral lesions? 詳細はこちら (PDF:1002KB)
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| 2023/08/04 |
Diagnostic criteria and endoscopic and histological findings of autoimmune gastritis in Japan 詳細はこちら (PDF:3130KB)
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| 2023/07/14 |
Cancer-Associated Fibroblasts Promote Aggressive Gastric Cancer Phenotypes via Heat Shock Factor1-Mediated Secretion of Extracellular Vesicles 詳細はこちら (PDF:388KB)
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| 2023/07/07 |
The Prognostic Values of HPV Genotypes and Tumor PD-L1 Expression in Patients With HPV-associated Endocervical Adenocarcinoma 詳細はこちら (PDF:633KB)
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| 2023/06/23 |
Single-cell transcriptome analysis of human skin identifies novel fibroblast subpopulation and enrichment of immune subsets in atopic dermatitis. 詳細はこちら (PDF:1722KB)
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| 2023/03/27 |
Metagenomic and metabolomic analyses reveal distinct stagespecific phenotypes of the gut microbiota in colorectal cancer 詳細はこちら (PDF:1933KB)
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| 2023/02/13 |
HPV51-associated Leiomyosarcoma A Novel Class of TP53/RB1-Wildtype Tumor With Predilection for the Female Lower Reproductive Tract 詳細はこちら (PDF:1295KB)
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| 2023/02/06 |
Tumor-Associated Macrophages Regulate PD-1/PD-L1 Immunosuppression 詳細はこちら (PDF:517KB)
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2022年
| 2022/10/31 |
Clinicopathological features of sclerosing angiomatoid nodular transformation of the spleen 詳細はこちら (PDF:379KB)
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| 2022/10/24 |
Oropharyngeal squamous cell carcinoma: p16/p53 immunohistochemistry as a strong predictor of HPV tumor status 詳細はこちら (PDF:1215KB)
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| 2022/10/17 |
Diffuse expression of MUC6 defines a distinct clinicopathological subset of pulmonary invasive mucinous adenocarcinoma 詳細はこちら (PDF:490KB)
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| 2022/09/12 |
Copy-number intratumor heterogeneity increases the risk of relapse in chemotherapy-naive stage II colon cancer 詳細はこちら (PDF:1226KB)
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| 2022/07/25 |
Association of High Tumor Mutation Burden in Non-Small Cell Lung Cancers With Increased Immune Infiltration and Improved Clinical Outcomes of PD-L1 Blockade Across PD-L1 Expression Levels 詳細はこちら (PDF:1435KB)
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| 2022/07/11 |
Exosomes in breast cancer - Mechanisms of Action and Clinical Potential 詳細はこちら (PDF:617KB)
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| 2022/07/04 |
Gastric epithelial neoplasm of fundic-gland mucosa lineage: proposal for a new classification in association with gastric adenocarcinoma of fundic-gland type 詳細はこちら (PDF:2086KB)
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| 2022/06/27 |
Cytoplasmic Pattern p53 Immunoexpression in Pelvic and Endometrial Carcinomas With TP53 Mutation Involving Nuclear Localization Domains: An Uncommon But Potential Diagnostic Pitfall With Clinical Implications 詳細はこちら (PDF:1878KB)
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| 2022/06/20 |
Cytokeratin 7 and cytokeratin 20 expression in cancer: A tissue microarray study on 15,424 cancers 詳細はこちら (PDF:3866KB)
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| 2022/06/13 |
Cellular engagement and interaction in the tumor microenvironment predict non-response to PD-1/PD-L1 inhibitors in metastatic non-small cell lung cancer. 詳細はこちら (PDF:1967KB)
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| 2022/06/06 |
RNF43 mutation analysis in serrated polyposis, sporadic serrated polyps and Lynch syndrome polyps 詳細はこちら (PDF:419KB)
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| 2022/05/16 |
Assessment of tumor depth in oral tongue squamous cell carcinoma with multiparametric MRI: correlation with pathology 詳細はこちら (PDF:265KB)
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| 2022/04/25 |
Immune Cell PD-L1 Colocalizes with Macrophages and Is Associated with Outcome in PD-1 Pathway Blockade Therapy 詳細はこちら (PDF:493KB)
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| 2022/04/04 |
Analysis of separate training and validation radical prostatectomy cohorts identifies 0.25mm diameter as an optimal definition for "large" cribriform prostatic adenocarcinoma 詳細はこちら (PDF:1581KB)
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| 2022/03/28 |
Modification of Pathologic T Classification for Non-small Cell Lung Cancer With Visceral Pleural Invasion 詳細はこちら (PDF:974KB)
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| 2022/03/14 |
Fundic gland polyps related to diverse aetiologies show subtle morphologic differences:A multicentre retrospective stud 詳細はこちら (PDF:874KB)
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| 2022/03/07 |
Breast adipose tissue macrophages (BATMs) have a stronger correlation with breast cancer survival than breast tumor stroma macrophages (BATMs) 詳細はこちら (PDF:7915KB)
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| 2022/02/28 |
Factors associated with myocardial SARS-CoV-2 infection, myocarditis, and cardiac inflammation in patients with COVID-19 詳細はこちら (PDF:717KB)
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| 2022/02/21 |
The ACE2-Ang-(1-7)-Mas Axis Modulates M1/M2 Macrophage Polarization to Relieve CLP-Induced Inflammation via TLR4-Madiated NFκb and MAPK Pathways 詳細はこちら (PDF:1450KB)
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| 2022/02/14 |
Meckel's Diverticulum with Dieulafoy's Lesion: A Cause of Severe Hematochezia. 詳細はこちら (PDF:364KB)
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| 2022/02/07 |
An unusual phenotype occurs in 15% of mismatch repair-deficient tumors and is associated with non-colorectal cancers and genetic syndromes 詳細はこちら (PDF:944KB)
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| 2022/01/31 |
A modified protein marker panel to identify four consensus molecular subtypes in colorectal cancer using immunohistochemistry 詳細はこちら (PDF:6798KB)
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| 2022/01/24 |
Heterogeneity of programmed death-ligand 1 expression and infiltrating lymphocytes in paired resected primary and metastatic non-small cell lung cancer. 詳細はこちら (PDF:1962KB)
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| 2022/01/17 |
Insights into Pathology and Pathogenesis of Coronavirus Disease 2019 from a Histopathological and Immunological Perspective 詳細はこちら (PDF:148KB)
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2021年
| 2021/12/20 |
The Expression of CD74-Regulated Inflammatory Markers in Stage IV Melanoma: Risk of CNS Metastasis and Patient Survival 詳細はこちら (PDF:225KB)
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| 2021/12/06 |
Validation of the International Tumor Budding Consensus Conference (ITBCC) 2016 recommendation in squamous cell carcinoma of the lung-a single-center analysis of 354 cases 詳細はこちら (PDF:2882KB)
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| 2021/11/29 |
Molecular characterization of ulcerative colitis-associated colorectal carcinomas 詳細はこちら (PDF:1180KB)
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| 2021/11/22 |
Analysis of tumor microenvironmental features to refine prognosis by T, N risk group in patients with stage III colon cancer 詳細はこちら (PDF:535KB)
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| 2021/11/01 |
DNA binding to TLR9 expressed by red blood cells promotes innate immune activation and anemia 詳細はこちら (PDF:385KB)
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| 2021/10/25 |
Mesonephric-like Carcinoma of the Endometrium: A Subset of Endometrial Carcinoma With an Aggressive Behavior 詳細はこちら (PDF:1505KB)
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| 2021/10/18 |
A template to quantify the location and density of CD3+ and CD8+ tumor-infiltrating lymphocytes in colon cancer by digital pathology on whole slides for objective, standardized immune score assessment 詳細はこちら (PDF:771KB)
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| 2021/10/11 |
Morphologic, Immunohistochemical, and Genetic Differences Between High-grade and Low-grade Fetal Adenocarcinomas of the Lung. 詳細はこちら (PDF:1857KB)
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| 2021/10/04 |
Colorectal Adenocarcinomas Harboring ALK Fusion Genes: A Clinicopathologic and Molecular Genetic Study of 12 Cases and Review of the Literature. 詳細はこちら (PDF:122KB)
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| 2021/09/13 |
Infiltration of tumor-associated macrophages is involved in tumor programmed death-ligand 1 expression in early lung adenocarcinoma. Cancer 詳細はこちら (PDF:310KB)
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| 2021/07/26 |
Genomic amplification of chromosome 20q13.33 is the early biomarker for the development of sporadic colorectal carcinoma 詳細はこちら (PDF:773KB)
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| 2021/07/12 |
Tumor spread through air spaces (STAS): prognostic significance of grading in non-small cell lung cancer 詳細はこちら (PDF:2602KB)
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| 2021/07/05 |
Pathological findings in the postmortem liver of patients with coronavirus disease 2019 (COVID19) 詳細はこちら (PDF:310KB)
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| 2021/06/28 |
Infiltrating Tumor Border Configuration is a Poor Prognostic Factor in Stage II and III Colon Adenocarcinoma 詳細はこちら (PDF:457KB)
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| 2021/06/14 |
The many faces of solitary fibrous tumor; diversity of histological features, differential diagnosis and role of molecular studies and surrogate markers in avoiding misdiagnosis and predicting the behavior 詳細はこちら (PDF:1342KB)
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| 2021/05/31 |
Prognostic value of macrophage polarization markers in epithelial neoplasms and melanoma. A systematic review and meta-analysis 詳細はこちら (PDF:811KB)
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| 2021/05/24 |
Chromogranin A Expression in Rectal Neuroendocrine Tumors Is Associated With More Aggressive Clinical Behavior and a Poorer Prognosis. 詳細はこちら (PDF:1126KB)
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| 2021/05/17 |
Recognition of filigree pattern expands the concept of micropapillary subtype in patients with surgically resected lung adenocarcinoma. 詳細はこちら (PDF:1895KB)
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| 2021/05/10 |
Malignant Gastrointestinal Neuroectodermal Tumor: Clinicopathologic, Immunohistochemical, and Molecular Analysis of 19 Cases. 詳細はこちら (PDF:141KB)
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| 2021/04/05 |
Clinico-pathologic predictors of patterns of residual disease following neoadjuvant chemotherapy for breast cancer 詳細はこちら (PDF:448KB)
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| 2021/03/29 |
Pulmonary post-mortem findings in a series of COVID-19 cases from northern Italy: a two-centre descriptive study 詳細はこちら (PDF:279KB)
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| 2021/03/15 |
Yap Aggrevates Inflammatory Bowel Disease by Regulation of M1/M2 Macrophage Polarization and Gut Microbial Homeostasis 詳細はこちら (PDF:1336KB)
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| 2021/03/08 |
Liver biopsy findings in patients on immune checkpoint inhibitors 詳細はこちら (PDF:756KB)
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| 2021/03/01 |
cIMPACT.NOW update 5: recommended grading criteria and terminologies for IDH.mutant astrocytomas 詳細はこちら (PDF:447KB)
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| 2021/02/22 |
Molecular characterization of colorectal adenomas reveals POFUT1 as a candidate driver of tumor progression 詳細はこちら (PDF:2.12MB)
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| 2021/02/15 |
Agrin in the Muscularis Mucosa Serves as a Biomarker Distinguishing Hyperplastic Polyps from Sessile Serrated Lesions 詳細はこちら (PDF:1.28MB)
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| 2021/02/08 |
Histopathologic Characterization of Myocarditis Associated With Immune Checkpoint Inhibitor Therapy 詳細はこちら (PDF:767KB)
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| 2021/02/01 |
Clinical significance of quantitative categorization of HER2 fluorescent in situ hybridization results in invasive breast cancer patients treated with HER2-targeted agents 詳細はこちら (PDF:326KB)
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| 2021/01/25 |
A pan-cancer analysis of PD-L1 immunohistochemistry and gene amplification, tumor mutation burden and microsatellite instability in 48,782 cases. 詳細はこちら (PDF:774KB)
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| 2021/01/18 |
Comparison of RNA In Situ Hybridization and Immunohistochemistry Techniques for the Detection and Localization of SARS-CoV-2 in Human Tissues. 詳細はこちら (PDF:326KB)
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