Journal Club



2024/02/16 Histone demethylase KDM5D upregulation drives sex differences in colon cancer
 詳細はこちら  (PDF:366KB)
2024/02/09 miRNA levels are associated with body mass index in endometrial cancer and may have implications for therapy.
 詳細はこちら  (PDF:1013KB)
2024/01/19 Patterns of transcription factor programs and immune pathway activation define four major subtypes of SCLC with distinct therapeutic vulnerabilities
 詳細はこちら  (PDF:1433KB)
2024/01/12 S100-stained perineural invasion is associated with worse prognosis in stage I/II colorectal cancer: Its possible association with immunosuppression in the tumor
 詳細はこちら  (PDF:973KB)


2023/12/15 p16 overexpression and Rb loss correlate with high-risk HPV infection in oropharyngeal squamous cell carcinoma
 詳細はこちら  (PDF:1973KB)
2023/12/01 Diagnostic challenges of intra-operative frozen consultation for gastrointestinal signet ring cell carcinoma
 詳細はこちら  (PDF:448KB)
2023/11/24 High-grade vulvar intraepithelial neoplasia: comprehensive characterization and long-term vulvar carcinoma risk
 詳細はこちら  (PDF:1859KB)
2023/11/17 Non-diffuse large B-cell lymphoma transformation from follicular lymphoma: a single-institution study of 19 cases
 詳細はこちら  (PDF:623KB)
2023/10/27 First-Line Genomic Profiling in Previously Untreated Advanced Solid Tumors for Identification of Targeted Therapy Opportunities.
 詳細はこちら  (PDF:1520KB)
2023/10/12 The risk of weekend biopsy: Impact of specimen source and fixation status on HER2 assessment in the treatment of advanced gastric cancer (The HER_WEEKEND study)
 詳細はこちら  (PDF:891KB)
2023/10/06 Worst pattern of invasion in oral squamous cell carcinoma is an independent prognostic factor.
 詳細はこちら  (PDF:875KB)
2023/09/22 Getting it Right the First Time: Frozen Sections for Diagnosing Necrotizing Soft Tissue Infections
 詳細はこちら  (PDF:1078KB)
2023/09/15 Cause of death and the autopsy rate in an elderly population.
 詳細はこちら  (PDF:794KB)
2023/09/08 Review of lymphoma in the duodenum: An update of diagnosis and management
 詳細はこちら  (PDF:1161KB)
2023/09/01 Hypothesis: HEG1 and claudin-4 staining will allow a diagnosis of epithelioid and biphasic mesothelioma versus non-small-cell lung carcinoma with only two stains in most cases
 詳細はこちら  (PDF:1185KB)
2023/08/25 Cancer-Associated Fibroblasts in Mycosis Fungoides Promote Tumor Cell Migration and Drug Resistance through CXCL12/CXCR4
 詳細はこちら  (PDF:558KB)
2023/08/18 Can dual staining with p16 and Ki67 be biomarkers of epithelial dysplasia in oral lesions?
 詳細はこちら  (PDF:1002KB)
2023/08/04 Diagnostic criteria and endoscopic and histological findings of autoimmune gastritis in Japan
 詳細はこちら  (PDF:3130KB)
2023/07/14 Cancer-Associated Fibroblasts Promote Aggressive Gastric Cancer Phenotypes via Heat Shock Factor1-Mediated Secretion of Extracellular Vesicles
 詳細はこちら  (PDF:388KB)
2023/07/07 The Prognostic Values of HPV Genotypes and Tumor PD-L1 Expression in Patients With HPV-associated Endocervical Adenocarcinoma
 詳細はこちら  (PDF:633KB)
2023/06/23 Single-cell transcriptome analysis of human skin identifies novel fibroblast subpopulation and enrichment of immune subsets in atopic dermatitis.
 詳細はこちら  (PDF:1722KB)
2023/03/27 Metagenomic and metabolomic analyses reveal distinct stagespecific phenotypes of the gut microbiota in colorectal cancer
 詳細はこちら  (PDF:1933KB)
2023/02/13 HPV51-associated Leiomyosarcoma A Novel Class of TP53/RB1-Wildtype Tumor With Predilection for the Female Lower Reproductive Tract
 詳細はこちら  (PDF:1295KB)
2023/02/06 Tumor-Associated Macrophages Regulate PD-1/PD-L1 Immunosuppression
 詳細はこちら  (PDF:517KB)


2022/10/31 Clinicopathological features of sclerosing angiomatoid nodular transformation of the spleen
 詳細はこちら  (PDF:379KB)
2022/10/24 Oropharyngeal squamous cell carcinoma: p16/p53 immunohistochemistry as a strong predictor of HPV tumor status
 詳細はこちら  (PDF:1215KB)
2022/10/17 Diffuse expression of MUC6 defines a distinct clinicopathological subset of pulmonary invasive mucinous adenocarcinoma
 詳細はこちら  (PDF:490KB)
2022/09/12 Copy-number intratumor heterogeneity increases the risk of relapse in chemotherapy-naive stage II colon cancer
 詳細はこちら  (PDF:1226KB)
2022/07/25 Association of High Tumor Mutation Burden in Non-Small Cell Lung Cancers With Increased Immune Infiltration and Improved Clinical Outcomes of PD-L1 Blockade Across PD-L1 Expression Levels
 詳細はこちら  (PDF:1435KB)
2022/07/11 Exosomes in breast cancer - Mechanisms of Action and Clinical Potential
 詳細はこちら  (PDF:617KB)
2022/07/04 Gastric epithelial neoplasm of fundic-gland mucosa lineage: proposal for a new classification in association with gastric adenocarcinoma of fundic-gland type
 詳細はこちら  (PDF:2086KB)
2022/06/27 Cytoplasmic Pattern p53 Immunoexpression in Pelvic and Endometrial Carcinomas With TP53 Mutation Involving Nuclear Localization Domains: An Uncommon But Potential Diagnostic Pitfall With Clinical Implications
 詳細はこちら  (PDF:1878KB)
2022/06/20 Cytokeratin 7 and cytokeratin 20 expression in cancer: A tissue microarray study on 15,424 cancers
 詳細はこちら  (PDF:3866KB)
2022/06/13 Cellular engagement and interaction in the tumor microenvironment predict non-response to PD-1/PD-L1 inhibitors in metastatic non-small cell lung cancer.
 詳細はこちら  (PDF:1967KB)
2022/06/06 RNF43 mutation analysis in serrated polyposis, sporadic serrated polyps and Lynch syndrome polyps
 詳細はこちら  (PDF:419KB)
2022/05/16 Assessment of tumor depth in oral tongue squamous cell carcinoma with multiparametric MRI: correlation with pathology
 詳細はこちら  (PDF:265KB)
2022/04/25 Immune Cell PD-L1 Colocalizes with Macrophages and Is Associated with Outcome in PD-1 Pathway Blockade Therapy
 詳細はこちら  (PDF:493KB)
2022/04/04 Analysis of separate training and validation radical prostatectomy cohorts identifies 0.25mm diameter as an optimal definition for "large" cribriform prostatic adenocarcinoma
 詳細はこちら  (PDF:1581KB)
2022/03/28 Modification of Pathologic T Classification for Non-small Cell Lung Cancer With Visceral Pleural Invasion
 詳細はこちら  (PDF:974KB)
2022/03/14 Fundic gland polyps related to diverse aetiologies show subtle morphologic differences:A multicentre retrospective stud
 詳細はこちら  (PDF:874KB)
2022/03/07 Breast adipose tissue macrophages (BATMs) have a stronger correlation with breast cancer survival than breast tumor stroma macrophages (BATMs)
 詳細はこちら  (PDF:7915KB)
2022/02/28 Factors associated with myocardial SARS-CoV-2 infection, myocarditis, and cardiac inflammation in patients with COVID-19
 詳細はこちら  (PDF:717KB)
2022/02/21 The ACE2-Ang-(1-7)-Mas Axis Modulates M1/M2 Macrophage Polarization to Relieve CLP-Induced Inflammation via TLR4-Madiated NFκb and MAPK Pathways
 詳細はこちら  (PDF:1450KB)
2022/02/14 Meckel's Diverticulum with Dieulafoy's Lesion: A Cause of Severe Hematochezia.
 詳細はこちら  (PDF:364KB)
2022/02/07 An unusual phenotype occurs in 15% of mismatch repair-deficient tumors and is associated with non-colorectal cancers and genetic syndromes
 詳細はこちら  (PDF:944KB)
2022/01/31 A modified protein marker panel to identify four consensus molecular subtypes in colorectal cancer using immunohistochemistry
 詳細はこちら  (PDF:6798KB)
2022/01/24 Heterogeneity of programmed death-ligand 1 expression and infiltrating lymphocytes in paired resected primary and metastatic non-small cell lung cancer.
 詳細はこちら  (PDF:1962KB)
2022/01/17 Insights into Pathology and Pathogenesis of Coronavirus Disease 2019 from a Histopathological and Immunological Perspective
 詳細はこちら  (PDF:148KB)


2021/12/20 The Expression of CD74-Regulated Inflammatory Markers in Stage IV Melanoma: Risk of CNS Metastasis and Patient Survival
 詳細はこちら  (PDF:225KB)
2021/12/06 Validation of the International Tumor Budding Consensus Conference (ITBCC) 2016 recommendation in squamous cell carcinoma of the lung-a single-center analysis of 354 cases
 詳細はこちら  (PDF:2882KB)
2021/11/29 Molecular characterization of ulcerative colitis-associated colorectal carcinomas
 詳細はこちら  (PDF:1180KB)
2021/11/22 Analysis of tumor microenvironmental features to refine prognosis by T, N risk group in patients with stage III colon cancer
 詳細はこちら  (PDF:535KB)
2021/11/01 DNA binding to TLR9 expressed by red blood cells promotes innate immune activation and anemia
 詳細はこちら  (PDF:385KB)
2021/10/25 Mesonephric-like Carcinoma of the Endometrium: A Subset of Endometrial Carcinoma With an Aggressive Behavior
 詳細はこちら  (PDF:1505KB)
2021/10/18 A template to quantify the location and density of CD3+ and CD8+ tumor-infiltrating lymphocytes in colon cancer by digital pathology on whole slides for objective, standardized immune score assessment
 詳細はこちら  (PDF:771KB)
2021/10/11 Morphologic, Immunohistochemical, and Genetic Differences Between High-grade and Low-grade Fetal Adenocarcinomas of the Lung.
 詳細はこちら  (PDF:1857KB)
2021/10/04 Colorectal Adenocarcinomas Harboring ALK Fusion Genes: A Clinicopathologic and Molecular Genetic Study of 12 Cases and Review of the Literature.
 詳細はこちら  (PDF:122KB)
2021/09/13 Infiltration of tumor-associated macrophages is involved in tumor programmed death-ligand 1 expression in early lung adenocarcinoma. Cancer
 詳細はこちら  (PDF:310KB)
2021/07/26 Genomic amplification of chromosome 20q13.33 is the early biomarker for the development of sporadic colorectal carcinoma
 詳細はこちら  (PDF:773KB)
2021/07/12 Tumor spread through air spaces (STAS): prognostic significance of grading in non-small cell lung cancer
 詳細はこちら  (PDF:2602KB)
2021/07/05 Pathological findings in the postmortem liver of patients with coronavirus disease 2019 (COVID19)
 詳細はこちら  (PDF:310KB)
2021/06/28 Infiltrating Tumor Border Configuration is a Poor Prognostic Factor in Stage II and III Colon Adenocarcinoma
 詳細はこちら  (PDF:457KB)
2021/06/14 The many faces of solitary fibrous tumor; diversity of histological features, differential diagnosis and role of molecular studies and surrogate markers in avoiding misdiagnosis and predicting the behavior
 詳細はこちら  (PDF:1342KB)
2021/05/31 Prognostic value of macrophage polarization markers in epithelial neoplasms and melanoma. A systematic review and meta-analysis
 詳細はこちら  (PDF:811KB)
2021/05/24 Chromogranin A Expression in Rectal Neuroendocrine Tumors Is Associated With More Aggressive Clinical Behavior and a Poorer Prognosis.
 詳細はこちら  (PDF:1126KB)
2021/05/17 Recognition of filigree pattern expands the concept of micropapillary subtype in patients with surgically resected lung adenocarcinoma.
 詳細はこちら  (PDF:1895KB)
2021/05/10 Malignant Gastrointestinal Neuroectodermal Tumor: Clinicopathologic, Immunohistochemical, and Molecular Analysis of 19 Cases.
 詳細はこちら  (PDF:141KB)
2021/04/05 Clinico-pathologic predictors of patterns of residual disease following neoadjuvant chemotherapy for breast cancer
 詳細はこちら  (PDF:448KB)
2021/03/29 Pulmonary post-mortem findings in a series of COVID-19 cases from northern Italy: a two-centre descriptive study
 詳細はこちら  (PDF:279KB)
2021/03/15 Yap Aggrevates Inflammatory Bowel Disease by Regulation of M1/M2 Macrophage Polarization and Gut Microbial Homeostasis
 詳細はこちら  (PDF:1336KB)
2021/03/08 Liver biopsy findings in patients on immune checkpoint inhibitors
 詳細はこちら  (PDF:756KB)
2021/03/01 cIMPACT.NOW update 5: recommended grading criteria and terminologies for IDH.mutant astrocytomas
 詳細はこちら  (PDF:447KB)
2021/02/22 Molecular characterization of colorectal adenomas reveals POFUT1 as a candidate driver of tumor progression
 詳細はこちら  (PDF:2.12MB)
2021/02/15 Agrin in the Muscularis Mucosa Serves as a Biomarker Distinguishing Hyperplastic Polyps from Sessile Serrated Lesions
 詳細はこちら  (PDF:1.28MB)
2021/02/08 Histopathologic Characterization of Myocarditis Associated With Immune Checkpoint Inhibitor Therapy
 詳細はこちら  (PDF:767KB)
2021/02/01 Clinical significance of quantitative categorization of HER2 fluorescent in situ hybridization results in invasive breast cancer patients treated with HER2-targeted agents
 詳細はこちら  (PDF:326KB)
2021/01/25 A pan-cancer analysis of PD-L1 immunohistochemistry and gene amplification, tumor mutation burden and microsatellite instability in 48,782 cases.
 詳細はこちら  (PDF:774KB)
2021/01/18 Comparison of RNA In Situ Hybridization and Immunohistochemistry Techniques for the Detection and Localization of SARS-CoV-2 in Human Tissues.
 詳細はこちら  (PDF:326KB)

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岩手医科大学医学部 病理診断学講座